Acth, the abbreviation for adrenocorticotropic hormone. Acth is produced by the anterior lobe of the pituitary gland. The bloodstream carries the hormone to the adrenal glands, situated just above the kidneys. There, acth stimulates the cortex (outer layer) of the adrenals to produce corticosterone and other hormones. If the pituitary does not produce sufficient acht, the adrenal core will become smaller and its output of hormones will decline.
Unlike some other hormones, acth has not yet been synthesized in the laboratory. It is isolated from the pituitary glands of cattle and pigs. Injected into humans. Acth is used to treat many diseases, including certain allergies and asthma. It has an anti-inflammation action which make it useful in the treatment of rheumatoid arthritis and rheumatic fever. Acth is being used experimentally in other illnesses.
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